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???DNA?????????????????????????????????DNA?mtDNA?????DNA?nDNA?????????????????. ??????????????mtDNA??????????????? 2021 ?2??13??2???78?Volume 13 Number 2 ... - ???????DNA double?strand breaks?DSBs??????. ??????????????????homology? directed repair?HDR??????????non?ho?. ???????? ??????????????HRR ?DNA ????????NHEJ?????. ??DSB ????[48?49]??????????????????????NHEJ. ?????????????DSB ????HRR Sirtuins??????DNA????????? - SciEngineSIRT6??????. ??????????????DNA??????. ?. DNA????????????????. Kaidi. ??[52]????, SIRT6????RPA???DNA?. ??????????? - ??????????????????. ????????????????????. ???????????????????. ?????????????????? ????????? - ????? ??. ???????????????????????????????????262. ???????? ?????????????????????????. ???. ????? ?????????????????????????????????????????. ???????????????????????????????????. ??? ??????????(??)???????????????????????????????????????????. ???????????????????????????? PREFACE ??????????????????????????????????????. ??????????????????????????????????? ?????????????????????????????????????????????????????. ??????????????????????????????????????. ???? 2022 annual reportOn April 6, 2023, Mr. XU Nuojin, an executive Director and the chairman of the Board, tendered his resignation to the Board and resigned as ?? ??. Anyang Guangming Mansion. ?????. Underground. ??. 98,709. Hebi. ??. Hebi No.7 Courtyard. ?????. Residential. ??. 30,711.
